Anxiety / Stress – Society of Cannabis Clinicians https://www.cannabisclinicians.org Educating Healthcare Professionals about the Medical Use of Cannabis Sun, 15 Oct 2023 02:34:43 +0000 en-US hourly 1 https://wordpress.org/?v=6.2.3 https://www.cannabisclinicians.org/wp-content/uploads/2020/07/cropped-scc-flavicon-32x32.png Anxiety / Stress – Society of Cannabis Clinicians https://www.cannabisclinicians.org 32 32 Anxiety severity and prescription medication utilization in first-time medical marijuana users https://www.cannabisclinicians.org/2023/10/14/anxiety-severity-and-prescription-medication-utilization-in-first-time-medical-marijuana-users/ Sun, 15 Oct 2023 02:34:43 +0000 https://www.cannabisclinicians.org/?p=29435 Anxiety and post-traumatic stress disorder (PTSD) are qualifying psychiatric conditions for medical marijuana (MM) treatment in Pennsylvania. This study examined baseline prevalence and changes in prescription anxiety medication use three months following MM treatment initiation among individuals with these qualifying conditions. The study sample was comprised of 108 adults with anxiety or PTSD as a referring condition; they were enrolled in a longitudinal study evaluating biopsychosocial outcomes in new MM patients. Consenting participants completed an assessment battery at baseline and Month 3 (n = 94, 87 % follow-up rate) that included a measure of anxiety severity and questions about current anxiety medication prescription and desired (baseline) and actual (Month 3) reductions in medication use.

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]]> Self-Reported Effects of Medical Cannabis on Illness Severity, Depression and Anxiety in Fibromyalgia Patients: A Large Retrospective Case Series https://www.cannabisclinicians.org/2023/08/26/self-reported-effects-of-medical-cannabis-on-illness-severity-depression-and-anxiety-in-fibromyalgia-patients-a-large-retrospective-case-series/ Sat, 26 Aug 2023 16:18:08 +0000 https://www.cannabisclinicians.org/?p=29123 To observe the effect of cannabis on fibromyalgia illness severity and related symptoms of depression and anxiety. A retrospective chart review was conducted to identify all patients who indicated fibromyalgia as a primary reason for seeking medical cannabis and completed at least 1 follow-up visit at Harvest Medicine clinics from January 2017 to July 2021. Data extracted from patient charts included Patient Health Questionnaire-9 (PHQ-9) scores, Generalized Anxiety Disorder-7 (GAD-7) scores, and self-reported illness severity scores. Changes in these scores between a patient’s intake and first follow-up visits were calculated and analyzed for significance overall and in different demographic subgroups. Patients for whom no follow-up data were available were excluded.

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]]> The Effectiveness and Adverse Events of Cannabidiol and Tetrahydrocannabinol Used in the Treatment of Anxiety Disorders in a PTSD Subpopulation: An Interim Analysis of an Observational Study https://www.cannabisclinicians.org/2023/07/22/the-effectiveness-and-adverse-events-of-cannabidiol-and-tetrahydrocannabinol-used-in-the-treatment-of-anxiety-disorders-in-a-ptsd-subpopulation-an-interim-analysis-of-an-observational-study/ Sat, 22 Jul 2023 15:31:38 +0000 https://www.cannabisclinicians.org/?p=28949 Anxiety is a condition for which current treatments are often limited by adverse events (AEs). Components of medicinal cannabis, cannabidiol (CBD) and tetrahydrocannabinol (THC), have been proposed as potential treatments for anxiety disorders, specifically posttraumatic stress disorder (PTSD). To evaluate quality-of-life outcomes after treatment with various cannabis formulations to determine the effectiveness and associated AEs.

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]]> Clinical outcome data of anxiety patients treated with cannabis-based medicinal products in the United Kingdom: a cohort study from the UK Medical Cannabis Registry https://www.cannabisclinicians.org/2023/06/17/clinical-outcome-data-of-anxiety-patients-treated-with-cannabis-based-medicinal-products-in-the-united-kingdom-a-cohort-study-from-the-uk-medical-cannabis-registry/ Sat, 17 Jun 2023 21:57:21 +0000 https://www.cannabisclinicians.org/?p=28856 Cannabis-based medicinal products (CBMPs) have been identified as novel therapeutics for generalised anxiety disorder (GAD) based on pre-clinical models; however, there is a paucity of high-quality evidence on their effectiveness and safety. This study aimed to evaluate the clinical outcomes of patients with GAD treated with dried flower, oil-based preparations, or a combination of both CBMPs. A prospective cohort study of patients with GAD (n = 302) enrolled in the UK Medical Cannabis Registry prescribed oil or flower-based CBMPs was performed. Primary outcomes were changes in generalised anxiety disorder-7 (GAD-7) questionnaires at 1, 3, and 6 months compared to baseline. Secondary outcomes were single-item sleep quality scale (SQS) and health-related quality of life index (EQ-5D-5L) questionnaires at the same time points. These changes were assessed by paired t-tests. Adverse events were assessed in line with CTCAE (Common Terminology Criteria for Adverse Events) v4.0.

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]]> Cannabis for Anxiety and PTSD https://www.cannabisclinicians.org/2023/03/25/cannabis-for-anxiety-and-ptsd/ Sun, 26 Mar 2023 00:24:59 +0000 https://www.cannabisclinicians.org/?p=28151 Anxiety disorders are the most common type of psychiatric disorders, and they’re one of the most common conditions for which people use cannabis. One review found that among 6665 cannabis users with data collected from 13 different studies, 52% of the subjects reported using cannabis for anxiety, making it the second most commonly treated symptom, following pain (1). Anxiety disorders come in many forms, including generalized anxiety, social anxiety, and panic disorders.

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]]> Cannabis containing equivalent concentrations of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) induces less state anxiety than THC-dominant cannabis https://www.cannabisclinicians.org/2022/11/04/cannabis-containing-equivalent-concentrations-of-delta-9-tetrahydrocannabinol-thc-and-cannabidiol-cbd-induces-less-state-anxiety-than-thc-dominant-cannabis/ Fri, 04 Nov 2022 23:37:01 +0000 https://www.cannabisclinicians.org/?p=27098 Delta-9-tetrahydrocannabinol (THC), an active component of cannabis, can cause anxiety in some users during intoxication. Cannabidiol (CBD), another constituent of cannabis, has anxiolytic properties suggesting that cannabis products containing CBD in addition to THC may produce less anxiety than THC-only products. Findings to date around this issue have been inconclusive and could conceivably depend on moderating factors such as baseline anxiety levels in users.

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]]> Systematic literature review of human studies assessing the efficacy of cannabidiol for social anxiety https://www.cannabisclinicians.org/2022/10/15/systematic-literature-review-of-human-studies-assessing-the-efficacy-of-cannabidiol-for-social-anxiety-2/ Sat, 15 Oct 2022 11:56:35 +0000 https://www.cannabisclinicians.org/?p=26943 The current review evaluates the potential of cannabidiol (CBD) as a promising pharmacotherapy for social anxiety disorder (SAD). Although a number of evidence-based treatments for SAD are available, less than a third of affected individuals experience symptom remission after one year of treatment. Therefore, improved treatment options are urgently needed, and CBD is one candidate medication that may have certain benefits over current pharmacotherapies, including the absence of sedating side effects, reduced abuse liability, and rapid course of action. The current review provides a brief overview of CBD's mechanisms of action, neuroimaging in SAD, and evidence for CBD's effects on the neural substrates of SAD, as well as systematically reviewing literature directly examining the efficacy of CBD for improving social anxiety among healthy volunteers and individuals with SAD

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]]> An investigation of cannabis use for insomnia in depression and anxiety in a naturalistic sample https://www.cannabisclinicians.org/2022/08/11/an-investigation-of-cannabis-use-for-insomnia-in-depression-and-anxiety-in-a-naturalistic-sample/ Thu, 11 Aug 2022 13:53:52 +0000 https://www.cannabisclinicians.org/?p=26644 Little is known about cannabis use for insomnia in individuals with depression, anxiety, and comorbid depression and anxiety. To develop a better understanding of distinct profiles of cannabis use for insomnia management, a retrospective cohort study was conducted on a large naturalistic sample.

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]]> Effects of Δ9-tetrahydrocannabinol on aversive memories and anxiety: a review from human studies https://www.cannabisclinicians.org/2022/03/14/effects-of-%ce%b49-tetrahydrocannabinol-on-aversive-memories-and-anxiety-a-review-from-human-studies/ Mon, 14 Mar 2022 22:58:19 +0000 https://www.cannabisclinicians.org/?p=26283 Posttraumatic stress disorder (PTSD) may stem from the formation of aberrant and enduring aversive memories. Some PTSD patients have recreationally used Cannabis, probably aiming at relieving their symptomatology. However, it is still largely unknown whether and how Cannabis or its psychotomimetic compound Δ9-tetrahydrocannabinol (THC) attenuates the aversive/traumatic memory outcomes. Here, we seek to review and discuss the effects of THC on aversive memory extinction and anxiety in healthy humans and PTSD patients.

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]]> Endocannabinoids, Cannabinoids and the Regulation of Anxiety https://www.cannabisclinicians.org/2021/06/22/endocannabinoids-cannabinoids-and-the-regulation-of-anxiety/ Tue, 22 Jun 2021 16:17:13 +0000 https://www.cannabisclinicians.org/?p=23419 Cannabis has been used for hundreds of years, with its ability to dampen feelings of anxiety often reported as a primary reason for use. Only recently has the specific role cannabinoids play in anxiety been thoroughly investigated. Here we discuss the body of evidence describing how endocannabinoids and exogenous cannabinoids are capable of regulating the generation and termination of anxiety states.

Objective: To determine the short-term effects of smoked marijuana on the viral load in HIV-infected patients.

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