Cytokines – Society of Cannabis Clinicians https://www.cannabisclinicians.org Educating Healthcare Professionals about the Medical Use of Cannabis Sat, 12 Nov 2022 13:43:57 +0000 en-US hourly 1 https://wordpress.org/?v=6.2.3 https://www.cannabisclinicians.org/wp-content/uploads/2020/07/cropped-scc-flavicon-32x32.png Cytokines – Society of Cannabis Clinicians https://www.cannabisclinicians.org 32 32 Medical Cannabis Use and Inflammatory Cytokines and Chemokines Among Adult Chronic Pain Patients https://www.cannabisclinicians.org/2022/11/12/medical-cannabis-use-and-inflammatory-cytokines-and-chemokines-among-adult-chronic-pain-patients/ Sat, 12 Nov 2022 13:43:57 +0000 https://www.cannabisclinicians.org/?p=27138 Utilizing cannabis as a therapeutic option for chronic pain (CP) has increased significantly. However, data regarding the potential immunomodulatory effects of cannabis in CP patients remain scarce. We aimed at exploring the relationship between cannabis use and inflammatory cytokines and chemokines among a cohort of CP patients

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]]> The effects of cannabinoids on the pharmacokinetics of indinavir and nelfinavir https://www.cannabisclinicians.org/2021/06/17/the-effects-of-cannabinoids-on-the-pharmacokinetics-of-indinavir-and-nelfinavir/ Thu, 17 Jun 2021 19:39:43 +0000 https://www.cannabisclinicians.org/?p=23353 Cannabinoids, including smoked marijuana and delta9-tetrahydrocannabinol (THC) (dronabinol, Marinol), have been used to treat human immunodeficiency virus-1 (HIV)-associated anorexia and weight loss. Concerns have been raised, however, that these compounds might have adverse effects on the immune system of subjects with HIV infection.

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]]> Short-term effects of cannabinoids on immune phenotype and function in HIV-1-infected patients https://www.cannabisclinicians.org/2021/06/17/short-term-effects-of-cannabinoids-on-immune-phenotype-and-function-in-hiv-1-infected-patients/ Thu, 17 Jun 2021 19:32:22 +0000 https://www.cannabisclinicians.org/?p=23349 Cannabinoids, including smoked marijuana and delta9-tetrahydrocannabinol (THC) (dronabinol, Marinol), have been used to treat human immunodeficiency virus-1 (HIV)-associated anorexia and weight loss. Concerns have been raised, however, that these compounds might have adverse effects on the immune system of subjects with HIV infection.

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]]> Therapeutic Prospects of Cannabinoids in the Immunomodulation of Prevalent Autoimmune Diseases https://www.cannabisclinicians.org/2021/06/03/therapeutic-prospects-of-cannabinoids-in-the-immunomodulation-of-prevalent-autoimmune-diseases/ Thu, 03 Jun 2021 19:07:57 +0000 https://www.cannabisclinicians.org/?p=23209 Cannabinoids such as ▵-9-THC and CBD can downregulate the immune response by modulating the endocannabinoid system. This modulation is relevant for the treatment of prevalent autoimmune diseases (ADs), such as multiple sclerosis (MS), systemic lupus erythematosus (SLE), diabetes mellitus type 1 (DMT1), and rheumatoid arthritis (RA). These conditions require new therapeutic options with fewer side effects for the control of the autoimmune response. Objective: to conduct a literature review of preclinical scientific evidence that supports further clinical investigations for the use of cannabinoids (natural or synthetic) as potential immunomodulators of the immune response in ADs.

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]]> The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities https://www.cannabisclinicians.org/2021/03/01/the-endocannabinoid-system-of-the-skin-in-health-and-disease-novel-perspectives-and-therapeutic-opportunities-2/ Mon, 01 Mar 2021 16:43:20 +0000 https://www.cannabisclinicians.org/?p=21875 The newly discovered endocannabinoid system (ECS; comprising the endogenous lipid mediators endocanna- binoids present in virtually all tissues, their G-protein- coupled cannabinoid receptors, biosynthetic pathways and metabolizing enzymes) has been implicated in multiple regulatory functions both in health and disease.

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]]> Cannabidiol Modulates Cytokine Storm in Acute Respiratory Distress Syndrome Induced by Simulated Viral Infection Using Synthetic RNA https://www.cannabisclinicians.org/2020/10/12/cannabidiol-modulates-cytokine-storm-in-acute-respiratory-distress-syndrome-induced-by-simulated-viral-infection-using-synthetic-rna/ Mon, 12 Oct 2020 17:48:34 +0000 https://www.cannabisclinicians.org/?p=20036 Authors: Hesam Khodadadi, Évila Lopes Salles, Abbas Jarrahi, Fairouz Chibane, Vincenzo Costigliola, Jack C Yu, Kumar Vaibhav, David C Hess, Krishnan M Dhandapani, Babak Baban Published in Cannabis and Cannabinoid...

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]]> A molecular basis for the anti-inflammatory and anti-fibrosis properties of cannabidiol https://www.cannabisclinicians.org/2020/09/10/a-molecular-basis-for-the-anti-inflammatory-and-anti-fibrosis-properties-of-cannabidiol/ Thu, 10 Sep 2020 18:53:56 +0000 https://www.cannabisclinicians.org/?p=19550 Authors: Falone Sunda, Afolake Arowolo Published in The FASEB Journal April 2020 Abstract Cannabidiol (CBD) is considered a non-psychoactive, antioxidant, and anti-inflammatory compound derived from the Cannabis sativa plant. There...

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]]> A molecular basis for the anti‐inflammatory and anti‐fibrosis properties of cannabidiol https://www.cannabisclinicians.org/2020/09/08/a-molecular-basis-for-the-anti%e2%80%90inflammatory-and-anti%e2%80%90fibrosis-properties-of-cannabidiol/ Tue, 08 Sep 2020 18:38:22 +0000 https://www.cannabisclinicians.org/?p=19499 Authors: Falone Sunda, Afolake Arowolo Published in The FASEB Journal September 2020 Abstract Cannabidiol (CBD) is considered a non‐psychoactive, antioxidant, and anti‐inflammatory compound derived from the Cannabis sativa plant. There...

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]]> Δ9‐Tetrahydrocannabinolic acid alleviates collagen‐induced arthritis: Role of PPARγ and CB1 receptors https://www.cannabisclinicians.org/2020/08/11/%ce%b49%e2%80%90tetrahydrocannabinolic-acid-alleviates-collagen%e2%80%90induced-arthritis-role-of-ppar%ce%b3-and-cb1-receptors-2/ Wed, 12 Aug 2020 02:19:30 +0000 https://www.cannabisclinicians.org/?p=19169 Authors: Belén Palomares, Martín Garrido‐Rodriguez, Claudia Gonzalo‐Consuegra, María Gómez‐Cañas, Suwipa Saen‐oon, Robert Soliva, Juan A. Collado, Javier Fernández‐Ruiz, Gaetano Morello, Marco A. Calzado, Giovanni Appendino, Eduardo Muñoz Published in British Journal...

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]]> Δ9‐Tetrahydrocannabinolic acid alleviates collagen‐induced arthritis: Role of PPARγ and CB1 receptors https://www.cannabisclinicians.org/2020/07/29/%ce%b49%e2%80%90tetrahydrocannabinolic-acid-alleviates-collagen%e2%80%90induced-arthritis-role-of-ppar%ce%b3-and-cb1-receptors/ Wed, 29 Jul 2020 20:06:57 +0000 https://www.cannabisclinicians.org/?p=18996 Author: Belén Palomares Martín Garrido‐Rodriguez Claudia Gonzalo‐Consuegra María Gómez‐Cañas Suwipa Saen‐oon Robert Soliva Juan A. Collado Javier Fernández‐Ruiz Gaetano Morello Marco A. Calzado Giovanni Appendino Eduardo Muñoz Published in British Pharmacological Society ...

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