Antiviral Agents – Society of Cannabis Clinicians https://www.cannabisclinicians.org Educating Healthcare Professionals about the Medical Use of Cannabis Thu, 08 Apr 2021 02:14:40 +0000 en-US hourly 1 https://wordpress.org/?v=6.2.3 https://www.cannabisclinicians.org/wp-content/uploads/2020/07/cropped-scc-flavicon-32x32.png Antiviral Agents – Society of Cannabis Clinicians https://www.cannabisclinicians.org 32 32 Cannabidiol Inhibits SARS-CoV-2 Replication and Promotes the Host Innate Immune Response https://www.cannabisclinicians.org/2021/03/29/cannabidiol-inhibits-sars-cov-2-replication-and-promotes-the-host-innate-immune-response/ Mon, 29 Mar 2021 15:46:51 +0000 https://www.cannabisclinicians.org/?p=22301 The rapid spread of COVID-19 underscores the need for new treatments. Here we report that cannabidiol (CBD), a compound produced by the cannabis plant, inhibits SARS-CoV-2 infection. CBD and its metabolite, 7-OH-CBD, but not congeneric cannabinoids, potently block SARS-CoV-2 replication in lung epithelial cells. CBD acts after cellular infection, inhibiting viral gene expression and reversing many effects of SARS-CoV-2 on host gene transcription. CBD induces interferon expression and up-regulates its antiviral signaling pathway.

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]]> Cannabidiol for Viral Diseases: Hype or Hope? https://www.cannabisclinicians.org/2020/07/15/cannabidiol-for-viral-diseases-hype-or-hope/ Wed, 15 Jul 2020 20:57:49 +0000 https://www.cannabisclinicians.org/?p=18820 Authors: Alex Mabou Tagne, Barbara Pacchetti, Mikael Sodergren, Marco Cosentino, and Franca Marino Published in Mary Ann Liebert, Inc Publishers June 2020 Abstract Background: The possibility of cannabidiol (CBD) to be...

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]]> Marijuana use in hepatitis C infection does not affect liver biopsy histology or treatment outcomes. https://www.cannabisclinicians.org/2014/07/01/marijuana-use-in-hepatitis-c-infection/ Tue, 01 Jul 2014 20:39:52 +0000 http://cannabisclinicians.org/?p=6366 Authors: Theresa Liu, Glen T Howell, Lucy Turner, Kimberley Corace, Gary Garber, Curtis Cooper
Canadian Journal of Gastroenterology & Hepatology, July-August 2014
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BACKGROUND: Marijuana smoking is prevalent among hepatitis C virus-infected patients. The literature assessing the influence of marijuana on liver disease progression and hepatitis C virus antiviral treatment outcomes is conflicting. METHODS: The authors evaluated hepatitis C...

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]]> Delta-9 tetrahydrocannabinol (THC) inhibits lytic replication of gamma oncogenic herpesviruses in vitro. https://www.cannabisclinicians.org/2004/09/15/thc-inhibits-replication-of-herpes-viruses-in-vitro/ Wed, 15 Sep 2004 17:03:11 +0000 http://cannabisclinicians.org/?p=10949 Authors: Maria M. Medveczky, Tracy A. Sherwood, Thomas W. Klein, Herman Friedman, Peter G. Medveczky
BMC Medicinevolume, 15 September 2004
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BACKGROUND: The major psychoactive cannabinoid compound of marijuana, delta-9 tetrahydrocannabinol (THC), has been shown to modulate immune responses and lymphocyte function. After primary infection the viral DNA genome of gamma herpesviruses persists in lymphoid cell nuclei i...

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