Kidney – Society of Cannabis Clinicians https://www.cannabisclinicians.org Educating Healthcare Professionals about the Medical Use of Cannabis Sat, 29 Apr 2023 02:36:12 +0000 en-US hourly 1 https://wordpress.org/?v=6.2.3 https://www.cannabisclinicians.org/wp-content/uploads/2020/07/cropped-scc-flavicon-32x32.png Kidney – Society of Cannabis Clinicians https://www.cannabisclinicians.org 32 32 CBGA ameliorates inflammation and fibrosis in nephropathy https://www.cannabisclinicians.org/2023/04/28/cbga-ameliorates-inflammation-and-fibrosis-in-nephropathy/ Sat, 29 Apr 2023 02:36:12 +0000 https://www.cannabisclinicians.org/?p=28468 Cannabidiol (CBD) is thought to have multiple biological effects, including the ability to attenuate inflammatory processes. Cannabigerols (CBGA and its decarboxylated CBG molecule) have pharmacological profiles similar to CBD. The endocannabinoid system has recently emerged to contribute to kidney disease, however, the therapeutic properties of cannabinoids in kidney disease remain largely unknown. In this study, we determined whether CBD and CBGA can attenuate kidney damage in an acute kidney disease model induced by the chemotherapeutic cisplatin. In addition, we evaluated the anti-fibrosis effects of these cannabinoids in a chronic kidney disease model induced by unilateral ureteral obstruction (UUO). We find that CBGA, but not CBD, protects the kidney from cisplatin-induced nephrotoxicity.

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]]> Cannabinoid-2 receptor activation ameliorates hepatorenal syndrome https://www.cannabisclinicians.org/2020/11/09/cannabinoid-2-receptor-activation-ameliorates-hepatorenal-syndrome/ Mon, 09 Nov 2020 21:46:03 +0000 https://www.cannabisclinicians.org/?p=20509 Authors: Eszter Trojnar, Katalin Erdelyi,Csaba Matyas, Suxian Zhao, Janos Paloczi, Partha Mukhopadhyay, Zoltan V.Varga, Gyorgy Hasko, Pal Pacher Published in Free Radical Biology and Medicine May 2020 Abstract Study rationale: Hepatorenal...

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