Cytokine – Society of Cannabis Clinicians https://www.cannabisclinicians.org Educating Healthcare Professionals about the Medical Use of Cannabis Sat, 12 Aug 2023 19:06:19 +0000 en-US hourly 1 https://wordpress.org/?v=6.2.3 https://www.cannabisclinicians.org/wp-content/uploads/2020/07/cropped-scc-flavicon-32x32.png Cytokine – Society of Cannabis Clinicians https://www.cannabisclinicians.org 32 32 Cannabinoids in the treatment of cancer anorexia and cachexia: where have we been, where are we going? https://www.cannabisclinicians.org/2023/08/12/cannabinoids-in-the-treatment-of-cancer-anorexia-and-cachexia-where-have-we-been-where-are-we-going/ Sat, 12 Aug 2023 19:06:19 +0000 https://www.cannabisclinicians.org/?p=29072 Cachexia-anorexia cancer syndrome remains an unmet clinical need with a dearth of treatment and no standard of care. Acting through the endocannabinoid system, cannabinoids are one potential cancer cachexia treatment. Herein the potential mechanisms for cannabinoids for cancer cachexia are discussed as are previous and ongoing clinical trials.

The post Cannabinoids in the treatment of cancer anorexia and cachexia: where have we been, where are we going? appeared first on Society of Cannabis Clinicians.

]]> Cannabidiol in the acute phase of Febrile Infection-Related Epilepsy Syndrome (FIRES) https://www.cannabisclinicians.org/2023/04/15/cannabidiol-in-the-acute-phase-of-febrile-infection-related-epilepsy-syndrome-fires/ Sun, 16 Apr 2023 02:49:33 +0000 https://www.cannabisclinicians.org/?p=28339 Febrile infection-related epilepsy syndrome (FIRES) is a prolonged refractory status epilepticus (SE) that develops among healthy individuals after a febrile infection.

FIRES treatment is challenging due to its poor response to anti-seizure medications (ASMs) and anesthetic drugs. The use of cannabidiol (CBD) as an adjunctive treatment has been suggested, albeit data about its role in the acute phase is lacking. This report describes the use of purified CBD in the acute phase of two pediatric cases of FIRES and their long-term outcome.

Both children were treated with several ASMs, immunomodulators, anesthetics, and non-pharmacological treatment (ketogenic diet). CBD was administered, as an adjunctive treatment, through nasogastric tube about 30 days after onset. SE resolved within three days of reaching the target dose and both were seizure-free for one year after.

Although it is difficult to define the extent to which each previous therapy contributed to recovery, in both cases CBD therapy was a turning point, reinforcing its potential role as add-on treatment in the acute phase of FIRES.

The post Cannabidiol in the acute phase of Febrile Infection-Related Epilepsy Syndrome (FIRES) appeared first on Society of Cannabis Clinicians.

]]>