Schizophrenia – Society of Cannabis Clinicians https://www.cannabisclinicians.org Educating Healthcare Professionals about the Medical Use of Cannabis Mon, 22 May 2023 01:02:18 +0000 en-US hourly 1 https://wordpress.org/?v=6.2.3 https://www.cannabisclinicians.org/wp-content/uploads/2020/07/cropped-scc-flavicon-32x32.png Schizophrenia – Society of Cannabis Clinicians https://www.cannabisclinicians.org 32 32 Association between cannabis use disorder and schizophrenia stronger in young males than in females https://www.cannabisclinicians.org/2023/05/21/association-between-cannabis-use-disorder-and-schizophrenia-stronger-in-young-males-than-in-females/ Mon, 22 May 2023 01:02:18 +0000 https://www.cannabisclinicians.org/?p=28660 Previous research suggests an increase in schizophrenia population attributable risk fraction (PARF) for cannabis use disorder (CUD). However, sex and age variations in CUD and schizophrenia suggest the importance of examining differences in PARFs in sex and age subgroups. We conducted a nationwide Danish register-based cohort study including all individuals aged 16–49 at some point during 1972–2021. CUD and schizophrenia status was obtained from the registers. Hazard ratios (HR), incidence risk ratios (IRR), and PARFs were estimated. Joinpoint analyses were applied to sex-specific PARFs.

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The therapeutic role of Cannabidiol in mental health: a systematic review https://www.cannabisclinicians.org/2022/03/14/the-therapeutic-role-of-cannabidiol-in-mental-health-a-systematic-review/ Mon, 14 Mar 2022 22:50:22 +0000 https://www.cannabisclinicians.org/?p=26278 The therapeutic application of cannabidiol (CBD) is gaining interest due to expanding evidence for its use.
Objective: To summarize the clinical outcomes, study designs and limitations for the use of CBD and nabiximols (whole plant extract from Cannabis sativa L. that has been purified into 1:1 ratio of CBD and delta-9- tetrahydrocannabinol) in the treatment of psychiatric disorders.

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Cannabidiol Cigarettes as Adjunctive Treatment for Psychotic Disorders – A Randomized, Open-Label Pilot-Study https://www.cannabisclinicians.org/2021/12/08/cannabidiol-cigarettes-as-adjunctive-treatment-for-psychotic-disorders-a-randomized-open-label-pilot-study/ Thu, 09 Dec 2021 02:10:40 +0000 https://www.cannabisclinicians.org/?p=25437 The main aim of the study was to clarify the antipsychotic potential of CBD used as adjunctive therapy simulating a naturalistic setting. Our trial is the first study evaluating the effects of smoked CBD-cigarettes as adjunctive therapy for psychotic symptoms.

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Opposite Roles for Cannabidiol and δ-9-Tetrahydrocannabinol in Psychotomimetic Effects of Cannabis Extracts: A Naturalistic Controlled Study https://www.cannabisclinicians.org/2021/09/01/opposite-roles-for-cannabidiol-and-%ce%b4-9-tetrahydrocannabinol-in-psychotomimetic-effects-of-cannabis-extracts-a-naturalistic-controlled-study/ Wed, 01 Sep 2021 14:38:24 +0000 https://www.cannabisclinicians.org/?p=24131 Although δ-9-tetrahydrocannabinol (THC), the main cannabinoid from the cannabis plant, is responsible for the psychotomimetic effects of cannabis, cannabidiol (CBD), the second most abundant cannabinoid in the cannabis plant, does not show any psychotomimetic effect. Cannabidiol has even been proposed to be antipsychotic and to counteract some of the psychotomimetic effects of THC. The aim of this study was to test the potential antipsychotomimetic effects of CBD.

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FURTHER EVIDENCE OF ANXIETY- AND DEPRESSION-LIKE BEHAVIOR FOR TOTAL GENETIC ABLATION OF CANNABINOID RECEPTOR TYPE 1 https://www.cannabisclinicians.org/2020/11/16/further-evidence-of-anxiety-and-depression-like-behavior-for-total-genetic-ablation-of-cannabinoid-receptor-type-1/ Mon, 16 Nov 2020 16:05:00 +0000 https://www.cannabisclinicians.org/?p=20587 Authors: Delia Soriano, Alicia Brusco, Laura Caltana Published in Behavioural Brain Research November 2020 Abstract Cannabinoid receptor type 1 (CB1R) is the most abundant cannabinoid receptor in central nervous system....

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The endocannabinoidome as a substrate for noneuphoric phytocannabinoid action and gut microbiome dysfunction in neuropsychiatric disorders https://www.cannabisclinicians.org/2020/10/06/the-endocannabinoidome-as-a-substrate-for-noneuphoric-phytocannabinoid-action-and-gut-microbiome-dysfunction-in-neuropsychiatric-disorders/ Tue, 06 Oct 2020 07:40:03 +0000 https://www.cannabisclinicians.org/?p=19870 Authors: Vincenzo Di Marzo, PhD Published in DIALOGUES IN CLINICAL NEUROSCIENCE 2020 Abstract The endocannabinoid (eCB) system encompasses the eCBs anandamide and 2-arachidonoylglycerol, their anabolic/catabolic enzymes, and the cannabinoid CB1...

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Cannabis and Psychosis: a Critical Overview of the Relationship https://www.cannabisclinicians.org/2020/07/22/cannabis-and-psychosis-a-critical-overview-of-the-relationship/ Wed, 22 Jul 2020 18:36:05 +0000 https://www.cannabisclinicians.org/?p=18904 Authors: Charles Ksir, Carl L Hart Published in Current Psychiatry Reports February 2016 Abstract Interest in the relationship between cannabis use and psychosis has increased dramatically in recent years, in part...

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