Fetus – Society of Cannabis Clinicians https://www.cannabisclinicians.org Educating Healthcare Professionals about the Medical Use of Cannabis Mon, 16 Oct 2023 11:53:05 +0000 en-US hourly 1 https://wordpress.org/?v=6.2.3 https://www.cannabisclinicians.org/wp-content/uploads/2020/07/cropped-scc-flavicon-32x32.png Fetus – Society of Cannabis Clinicians https://www.cannabisclinicians.org 32 32 The placental disposition of cannabidiol: an ex vivo perfusion study https://www.cannabisclinicians.org/2023/10/16/the-placental-disposition-of-cannabidiol-an-ex-vivo-perfusion-study/ Mon, 16 Oct 2023 11:53:05 +0000 https://www.cannabisclinicians.org/?p=29440 In the absence of safety data in humans, the use of cannabidiol (CBD) is not recommended during pregnancy. Yet >50% of pregnancies in women with epilepsy are unintended, making fetal exposure to CBD possible. As a small-molecule, highly lipid-soluble drug, CBD is likely to distribute into the placenta and cross it. To estimate the placental distribution profile of CBD and its potential short-term placental effects, we conducted an ex vivo perfusion study in human placentas.

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]]> The endocannabinoid-CB(1) receptor system in pre- and postnatal life. https://www.cannabisclinicians.org/2004/10/01/the-endocannabinoid-cb1-receptor-system-in-pre-and-postnatal-life/ Fri, 01 Oct 2004 14:33:01 +0000 https://www.cannabisclinicians.org/?p=15590 Authors: Ester Fride
European Journal of Pharmacology, October 2004
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Recent research suggests that the endogenous cannabinoids ("endocannabinoids") and their cannabinoid receptors have a major influence during pre- and postnatal development. First, high levels of the endocannaboid anandamide and cannabinoid receptors are present in the preimpla...

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