Pre-symptomatic treatment – Society of Cannabis Clinicians https://www.cannabisclinicians.org Educating Healthcare Professionals about the Medical Use of Cannabis Thu, 19 Oct 2023 00:26:27 +0000 en-US hourly 1 https://wordpress.org/?v=6.2.3 https://www.cannabisclinicians.org/wp-content/uploads/2020/07/cropped-scc-flavicon-32x32.png Pre-symptomatic treatment – Society of Cannabis Clinicians https://www.cannabisclinicians.org 32 32 Updated clinical recommendations for the management of tuberous sclerosis complex associated epilepsy https://www.cannabisclinicians.org/2023/10/18/updated-clinical-recommendations-for-the-management-of-tuberous-sclerosis-complex-associated-epilepsy/ Thu, 19 Oct 2023 00:26:27 +0000 https://www.cannabisclinicians.org/?p=29468 Children with tuberous sclerosis complex (TSC), may experience a variety of seizure types in the first year of life, most often focal seizure sand epileptic spasms. Drug resistance is seen early in many patients, and the management of TSC associated epilepsy remain a major challenge for clinicians. In 2018 clinical recommendations for the management of TSC associated epilepsy were published by a panel of European experts. In the last five years considerable progress has been made in understanding the neurobiology of epileptogenesis and three interventional randomized controlled trials have changed the therapeutic approach for the management of TSC associated epilepsy. Pre-symptomatic treatment with vigabatrin may delay seizure onset, may reduce seizure severity and reduce the risk of epileptic encephalopathy.

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