Neuropathic Pain – Society of Cannabis Clinicians https://www.cannabisclinicians.org Educating Healthcare Professionals about the Medical Use of Cannabis Mon, 02 Oct 2023 20:58:11 +0000 en-US hourly 1 https://wordpress.org/?v=6.2.3 https://www.cannabisclinicians.org/wp-content/uploads/2020/07/cropped-scc-flavicon-32x32.png Neuropathic Pain – Society of Cannabis Clinicians https://www.cannabisclinicians.org 32 32 Cannabis constituents for chronic neuropathic pain; reconciling the clinical and animal evidence https://www.cannabisclinicians.org/2023/10/02/cannabis-constituents-for-chronic-neuropathic-pain-reconciling-the-clinical-and-animal-evidence/ Mon, 02 Oct 2023 20:58:11 +0000 https://www.cannabisclinicians.org/?p=29330 Chronic neuropathic pain is a debilitating pain syndrome caused by damage to the nervous system that is poorly served by current medications. Given these problems, clinical studies have pursued extracts of the plant Cannabis sativa as alternative treatments for this condition. The vast majority of these studies have examined can- nabinoids which contain the psychoactive constituent delta-9-tetrahydrocannabinol (THC). While there have been some positive findings, meta-analyses of this clinical work indicates that this effectiveness is limited and hampered by side-effects. This review focuses on how recent preclinical studies have predicted the clinical limita- tions of THC-containing cannabis extracts, and importantly, point to how they might be improved. This work highlights the importance of targeting channels and recep- tors other than cannabinoid CB1 receptors which mediate many of the side-effects of cannabis.

The post Cannabis constituents for chronic neuropathic pain; reconciling the clinical and animal evidence appeared first on Society of Cannabis Clinicians.

]]> Medical Cannabis Alleviates Chronic Neuropathic Pain Effectively and Sustainably without Severe Adverse Effect: A Retrospective Study on 99 Cases https://www.cannabisclinicians.org/2023/09/20/medical-cannabis-alleviates-chronic-neuropathic-pain-effectively-and-sustainably-without-severe-adverse-effect-a-retrospective-study-on-99-cases/ Thu, 21 Sep 2023 00:24:25 +0000 https://www.cannabisclinicians.org/?p=29246 Medical cannabis may provide a treatment option for chronic neuropathic pain. However, empirical disease-specific data are scarce. This is a retrospective observational study including 99 patients with chronic neuropathic pain. These patients received medical cannabis by means of inhaling dried flowers with tetrahydrocannabinol content of <12–22% at a maximal daily dose of 0.15–1 g. Up to six follow-ups were carried out at intervals of 4–6 weeks. Pain severity, sleep disturbance, general improvement, side effects, and therapy tolerance at the follow-up consultations were assessed in interviews and compared with the baseline data using non-parametric Wilcoxon signed-rank test.

The post Medical Cannabis Alleviates Chronic Neuropathic Pain Effectively and Sustainably without Severe Adverse Effect: A Retrospective Study on 99 Cases appeared first on Society of Cannabis Clinicians.

]]> Cannabinoids as a Potential Alternative to Opioids in the Management of Various Pain Subtypes: Benefits, Limitations, and Risks https://www.cannabisclinicians.org/2023/03/04/cannabinoids-as-a-potential-alternative-to-opioids-in-the-management-of-various-pain-subtypes-benefits-limitations-and-risks/ Sun, 05 Mar 2023 02:42:40 +0000 https://www.cannabisclinicians.org/?p=27954 Pain is a global phenomenon encompassing many subtypes that include neuropathic, musculoskeletal, acute postoperative, cancer, and geriatric pain. Traditionally, opioids have been a mainstay pharmacological agent for managing many types of pain. However, opioids have been a subject of controversy with increased addiction, fatality rates, and cost burden on the US healthcare system. Cannabinoids have emerged as a potentially favorable alternative or adjunctive treatment for various types of acute and chronic pain. This narrative review seeks to describe the efficacy, risks, and benefits of cannabinoids as an adjunct or even potential replacement for opioids in the treatment of various subtypes of pain.

The post Cannabinoids as a Potential Alternative to Opioids in the Management of Various Pain Subtypes: Benefits, Limitations, and Risks appeared first on Society of Cannabis Clinicians.

]]> Use of cannabinoids in cancer patients: A Society of Gynecologic Oncology (SGO) clinical practice statement. https://www.cannabisclinicians.org/2020/01/10/use-of-cannabinoids-in-cancer-patients-a-society-of-gynecologic-oncology-sgo-clinical-practice-statement/ Sat, 11 Jan 2020 02:48:41 +0000 https://www.cannabisclinicians.org/?p=17501 Authors: B. Whitcomb, C. Lutman, M. Pearl, E. Medlin, E. Prendergast, K. Robison, W. Burke
Gynecologic Oncology, 10 January 2020
---
Tetrahydrocannabinol (THC), cannabidiol (CBD) and cannabinol (CBN) affect the human endocannabinoid system. Cannabinoids reduce chemotherapy induced nausea or vomiting (CINV) and neuropathic pain. Each state has its own regulations for medical and recreational cannabis use. Ef...

The post Use of cannabinoids in cancer patients: A Society of Gynecologic Oncology (SGO) clinical practice statement. appeared first on Society of Cannabis Clinicians.

]]> Role of Cannabinoids in Pain Management https://www.cannabisclinicians.org/2013/01/01/role-of-cannabinoids-in-pain-management/ Tue, 01 Jan 2013 16:47:41 +0000 http://cannabisclinicians.org/?p=8469 Authors: Ethan B. Russo, Andrea G. Hohmann
Comprehensive Treatment of Chronic Pain by Medical, Interventional, and Integrative Approaches, 2013
---
It is a curious fact that we owe a great deal of our insight into pharmacological treatment of pain to the plant world. Willow bark from Salix spp. led to development of aspirin and eventual elucidation of the analgesic effects of prostaglandins and their role in inflammation...

The post Role of Cannabinoids in Pain Management appeared first on Society of Cannabis Clinicians.

]]>