Herpes – Society of Cannabis Clinicians https://www.cannabisclinicians.org Educating Healthcare Professionals about the Medical Use of Cannabis Sat, 29 Apr 2023 02:42:57 +0000 en-US hourly 1 https://wordpress.org/?v=6.2.3 https://www.cannabisclinicians.org/wp-content/uploads/2020/07/cropped-scc-flavicon-32x32.png Herpes – Society of Cannabis Clinicians https://www.cannabisclinicians.org 32 32 Antiviral activities of hemp cannabinoids https://www.cannabisclinicians.org/2023/04/28/antiviral-activities-of-hemp-cannabinoids/ Sat, 29 Apr 2023 02:42:17 +0000 https://www.cannabisclinicians.org/?p=28472 Hemp is an understudied source of pharmacologically active compounds and many unique plant secondary metabolites including more than 100 cannabinoids. After years of legal restriction, research on hemp has recently demonstrated antiviral activities in silico, in vitro, and in vivo for cannabidiol (CBD), Δ9-tetrahydrocannabinol (Δ9-THC), cannabidiolic acid (CBDA), cannabigerolic acid (CBGA), and several other cannabinoids against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), human immunodeficiency virus (HIV), and γ-herpes viruses. Mechanisms of action include inhibition of viral cell entry, inhibition of viral proteases, and stimulation of cellular innate immune responses. The anti-inflammatory properties of cannabinoids are also under investigation for mitigating the cytokine storm of COVID-19 and controlling chronic inflammation in people living with HIV. Retrospective clinical studies support antiviral activities of CBD, Δ9-THC, and cannabinoid mixtures as do some prospective clinical trials, but appropriately designed clinical trials of safety and efficacy of antiviral cannabinoids are urgently needed.

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]]> Cannabidiol for Viral Diseases: Hype or Hope? https://www.cannabisclinicians.org/2020/07/15/cannabidiol-for-viral-diseases-hype-or-hope/ Wed, 15 Jul 2020 20:57:49 +0000 https://www.cannabisclinicians.org/?p=18820 Authors: Alex Mabou Tagne, Barbara Pacchetti, Mikael Sodergren, Marco Cosentino, and Franca Marino Published in Mary Ann Liebert, Inc Publishers June 2020 Abstract Background: The possibility of cannabidiol (CBD) to be...

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]]> Delta-9 tetrahydrocannabinol (THC) inhibits lytic replication of gamma oncogenic herpesviruses in vitro. https://www.cannabisclinicians.org/2004/09/15/thc-inhibits-replication-of-herpes-viruses-in-vitro/ Wed, 15 Sep 2004 17:03:11 +0000 http://cannabisclinicians.org/?p=10949 Authors: Maria M. Medveczky, Tracy A. Sherwood, Thomas W. Klein, Herman Friedman, Peter G. Medveczky
BMC Medicinevolume, 15 September 2004
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BACKGROUND: The major psychoactive cannabinoid compound of marijuana, delta-9 tetrahydrocannabinol (THC), has been shown to modulate immune responses and lymphocyte function. After primary infection the viral DNA genome of gamma herpesviruses persists in lymphoid cell nuclei i...

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