Dronabinol – Society of Cannabis Clinicians https://www.cannabisclinicians.org Educating Healthcare Professionals about the Medical Use of Cannabis Sat, 17 Jun 2023 21:36:51 +0000 en-US hourly 1 https://wordpress.org/?v=6.2.3 https://www.cannabisclinicians.org/wp-content/uploads/2020/07/cropped-scc-flavicon-32x32.png Dronabinol – Society of Cannabis Clinicians https://www.cannabisclinicians.org 32 32 Cannabinoids in hyperhidrosis https://www.cannabisclinicians.org/2023/06/17/cannabinoids-in-hyperhidrosis/ Sat, 17 Jun 2023 21:36:51 +0000 https://www.cannabisclinicians.org/?p=28850 Hyperhidrosis can significantly curtail patient quality of life, from debilitating physical symptoms to social stigmatization and reduced life opportunities. Current treatments often prove unsatisfactory, especially in sufferers of generalized hyperhidrosis. In this open trial, we present the case of a refractory generalized hyperhidrosis treated with cannabinoids. We found a remarkable reduction in the volume of sweat and an improvement to the patient’s quality of life using this novel low-cost and low-impact approach.

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]]> Cannabis labelling is associated with genetic variation in terpene synthase genes https://www.cannabisclinicians.org/2021/11/17/cannabis-labelling-is-associated-with-genetic-variation-in-terpene-synthase-genes/ Thu, 18 Nov 2021 01:01:06 +0000 https://www.cannabisclinicians.org/?p=25184 Analysis of over 100 Cannabis samples quantified for terpene and cannabinoid content and genotyped for over 100,000 single nucleotide polymorphisms indicated that Sativa- and Indica-labelled samples were genetically indistinct on a genome-wide scale. Instead, we found that Cannabis labelling was associated with variation in a small number of terpenes whose concentrations are controlled by genetic variation at tandem arrays of terpene synthase genes.

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]]> Effects of cannabis ingestion on endometriosis-associated pelvic pain and related symptoms https://www.cannabisclinicians.org/2021/11/10/effects-of-cannabis-ingestion-on-endometriosis-associated-pelvic-pain-and-related-symptoms/ Thu, 11 Nov 2021 01:03:22 +0000 https://www.cannabisclinicians.org/?p=25123 The use of cannabis for symptoms of endometriosis was investigated utilising retrospective archival data from Strainprint Technologies Ltd., a Canadian data technology company with a mobile phone application that tracks a range of data including dose, mode of administration, chemovar and their effects on various self-reported outcomes, including pelvic pain.

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]]> Cannabis Glandular Trichomes: A Cellular Metabolite Factory https://www.cannabisclinicians.org/2021/10/20/cannabis-glandular-trichomes-a-cellular-metabolite-factory/ Wed, 20 Oct 2021 19:34:37 +0000 https://www.cannabisclinicians.org/?p=24788 While growers tend to focus on improving whole flower yields, our understanding of the “goldmines” of the plant – the trichomes – is limited despite their being the true source of revenue for a multi-billion-dollar industry. This review aims to provide an overview of our current understanding of cannabis glandular trichomes and their metabolite products in order to identify current gaps in knowledge and to outline future research directions.

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]]> The Effect of Medical Cannabis on Pain Level and Quality of Sleep among Rheumatology Clinic Outpatients https://www.cannabisclinicians.org/2021/10/20/the-effect-of-medical-cannabis-on-pain-level-and-quality-of-sleep-among-rheumatology-clinic-outpatients/ Wed, 20 Oct 2021 19:19:38 +0000 https://www.cannabisclinicians.org/?p=24781 Medical cannabis (MC) is becoming increasingly popular for the treatment of chronic pain conditions. In this study, we evaluated the effect of MC treatment on pain level and quality of sleep of patients with different medical conditions at the rheumatology clinic.

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]]> Practical Strategies Using Medical Cannabis to Reduce Harms Associated With Long Term Opioid Use in Chronic Pain https://www.cannabisclinicians.org/2021/10/20/practical-strategies-using-medical-cannabis-to-reduce-harms-associated-with-long-term-opioid-use-in-chronic-pain/ Wed, 20 Oct 2021 18:03:36 +0000 https://www.cannabisclinicians.org/?p=24768 Chronic non-cancer pain (CNCP) is estimated to affect 20% of the adult population. Current United States and Canadian Chronic non-cancer pain guidelines recommend careful reassessment of the risk-benefit ratio for doses greater than 90 mg morphine equivalent dose (MED), due to low evidence for improved pain efficacy at higher morphine equivalent dose and a significant increase in morbidity and mortality. There are a number of human studies demonstrating cannabis opioid synergy. This preliminary evidence suggests a potential role of cannabis as an adjunctive therapy with or without opioids to optimize pain control.

To describe the prevalence and patterns of cannabidiol (CBD) use in women with co-existing chronic pelvic pain (CPP) and fibromyalgia, and to evaluate characteristics associated with pain improvement.
To describe the prevalence and patterns of cannabidiol (CBD) use in women with co-existing chronic pelvic pain (CPP) and fibromyalgia, and to evaluate characteristics associated with pain improvement.

To describe the prevalence and patterns of cannabidiol (CBD) use in women with co-existing chronic pelvic pain (CPP) and fibromyalgia, and to evaluate characteristics associated with pain improvement.

Many cannabinoids display promising non-hallucinogenic bioactivities that are determined by the variable nature of the side chain and prenyl group defined by the enzymes involved in their synthesis.

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]]> Phytocannabinoids: Origins and Biosynthesis https://www.cannabisclinicians.org/2021/09/16/phytocannabinoids-origins-and-biosynthesis/ Thu, 16 Sep 2021 15:27:11 +0000 https://www.cannabisclinicians.org/?p=24341 hytocannabinoids are bioactive terpenoids that were thought to be exclusive to Cannabis sativa, but have now also been discovered in Rhododendron species, some legumes, the liverwort genus Radula, and some fungi.

Many cannabinoids display promising non-hallucinogenic bioactivities that are determined by the variable nature of the side chain and prenyl group defined by the enzymes involved in their synthesis.

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]]> Opposite Roles for Cannabidiol and δ-9-Tetrahydrocannabinol in Psychotomimetic Effects of Cannabis Extracts: A Naturalistic Controlled Study https://www.cannabisclinicians.org/2021/09/01/opposite-roles-for-cannabidiol-and-%ce%b4-9-tetrahydrocannabinol-in-psychotomimetic-effects-of-cannabis-extracts-a-naturalistic-controlled-study/ Wed, 01 Sep 2021 14:38:24 +0000 https://www.cannabisclinicians.org/?p=24131 Although δ-9-tetrahydrocannabinol (THC), the main cannabinoid from the cannabis plant, is responsible for the psychotomimetic effects of cannabis, cannabidiol (CBD), the second most abundant cannabinoid in the cannabis plant, does not show any psychotomimetic effect. Cannabidiol has even been proposed to be antipsychotic and to counteract some of the psychotomimetic effects of THC. The aim of this study was to test the potential antipsychotomimetic effects of CBD.

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]]> The Effectiveness of Cannabis and Cannabis Derivatives in Treating Lower Back Pain in the Aged Population: A Systematic Review https://www.cannabisclinicians.org/2021/09/01/the-effectiveness-of-cannabis-and-cannabis-derivatives-in-treating-lower-back-pain-in-the-aged-population-a-systematic-review/ Wed, 01 Sep 2021 14:28:03 +0000 https://www.cannabisclinicians.org/?p=24126 Cannabis is increasingly used in the management of pain, though minimal research exists to sup- port its use since approval. Reduction in stigma has led to a growing interest in pharmaceutical cannabinoids as a pos- sible treatment for lower back pain (LBP). The objective of this review was to assess the role and efficacy of cannabis and its derivatives in the management of LBP and compile global data related to the role of cannabis in the manage- ment of LBP in an aging population

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]]> Preoperative administration of cannabidiol (CBD) in healthy dogs undergoing elective surgery in Colombia: 16 Cases https://www.cannabisclinicians.org/2021/08/26/preoperative-administration-of-cannabidiol-cbd-in-healthy-dogs-undergoing-elective-surgery-in-colombia-16-cases/ Thu, 26 Aug 2021 16:41:32 +0000 https://www.cannabisclinicians.org/?p=24080 . The objective of this study is retrospectively review the effect of a single dose administration of two pharmaceutical grade CBD oils on basic cardiorespiratory parameters and anesthetic recovery of dogs undergoing elective surgery. Complete medical and anesthesia records of healthy dogs of the spay/neuter program of Corporaciòn Universitaria Santa Rosa de Cabal UNISARC whose owners approved a preoperative single dose of CBD were included for analysis. Dogs were considered clinically healthy based on physical examination, complete hemogram and serum creatinine and ALT concentration

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